Functional MR Imaging (BOLD and Resting States). Clinical and Research Applications

摘要

Since the first experiments with the blood oxygen level contrast (BOLD) by Ogawa et al. in 1990, functional MRI has been a basic tool in the research environment and in the clinical world as well as. In this plenary lecture we will first give an introduction on the physics as well as the physiology behind the BOLD effect. Then we will explain how standard functional (fMRI) and resting states (RS) experiments are performed and data is analyzed. After, we will highlight the clinical as well as the research applications of these techniques. The function of a medical physicist in this environment will be then described and finally, we will present some examples of the research developed by our collaborators in Mexico.