EFFECTS OF A SECOND CHALLENGE WITH ACTINOBACILLUS PLEUROPNEUMONIAE IN PIGS TREATED WITH DIFFERENT ANTIBIOTICS AT THE PRIMARY INFECTION

摘要

Acute actinobacillosis causes respiratory disease where affected pigs rapidly develop clinical signs and serum antibodies (1). Surviving pigs develop protection towards re-infections. Antimicrobial treatments will reduce the signs of disease, but differ in efficacy. Less effective drugs hardly affect the course of disease; medium effective drugs have good clinical effect but only prevent pathological lesions and seroconversion to a limited extent; while highly effective drugs may prevent seroconversion and the development of clinical signs (2, 4). The aim of this trial was to study the resistance towards re-infection in pigs treated with drugs of different efficacy following a primary exposure to App2.