Constructing phylogenetic tree based on three-parameter model

摘要

Neighbor Joining Algorithm (Neighbor-Joining or NJ) is a common way to construct phylogenetic trees. To enhance the accuracy of constructing the phylogenetic trees, we use the Kimura three-parameter model to calculate the distance between sequences, raising a way to improve NJ. By computer simulation, we made a comparative analysis of the accuracy among the improved NJ. UPGMA, and the original NJ, the result showing that the improved NJ is superior to UPGMA and the original NJ.