QUANTITATIVE RISK ASSESSMENT OF ANTIMICROBIALS IN THE FEED TO FOOD CHAIN

摘要

A feed to food chain risk assessment model was developed to assess the fate of the contaminats triclosan (TCC) and triclocarban (TCC) from spreading biosolids on land. The model considered parameters such as; concentration in soil, plant uptake, bio-transfer into milk and beef, and resulting human exposure. Transfer of TCS and TCC from biosolid application, biotransfer into milk and beef followed by human consumption was considered minimal. From the scenarios considered, the greatest exposure of TCC was through milk for infants and beef for teens (mean values 1.14 × 10~(-7) mg kg~(-1) bw d~(-1), 7.41 × 10~(-8) mg kg~(-1) bw d~(-1), respectively). TCS and TCC levels were well below the estimated acceptable daily intake (ADI). Therefore, the concentrations of TCS and TCC in beef and milk represent a minor exposure pathway for humans.