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Using Constraint Logic Programming for the Verification of Customized Decision Models for Clinical Guidelines

机译:使用约束逻辑编程验证临床指南的定制决策模型

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Computer-interpretable implementations of clinical guidelines (CIGs) add knowledge that is outside the scope of the original guideline. This knowledge can customize CIGs to patients' psycho-social context or address comorbidities that are common in the local population, potentially increasing standardization of care and patient compliance. We developed a two-layered contextual decision-model based on the PROforma CIG formalism that separates the primary knowledge of the original guideline from secondary arguments for or against specific recommendations. In this paper we show how constraint logic programming can be used to verify the layered model for two essential properties: (1) secondary arguments do not rule in recommendations that are ruled out in the original guideline, and (2) the CIG is complete in providing recommendation(s) for any combination of patient data items considered. We demonstrate our approach when applied to the asthma domain.
机译:临床指南(CIG)的计算机可解释实现增加了原始指南范围之外的知识。这些知识可以根据患者的社会心理背景定制CIG,或解决当地人群中常见的合并症,从而有可能提高护理和患者依从性的标准化程度。我们基于PROforma CIG形式主义开发了一个两层的上下文决策模型,该模型将原始指南的主要知识与针对特定建议的次要论点分开。在本文中,我们展示了如何使用约束逻辑编程来验证具有两个基本属性的分层模型:(1)辅助参数不排除原始准则中所排除的建议,以及(2)CIG是完整的为所考虑的患者数据项的任何组合提供建议。当应用于哮喘领域时,我们证明了我们的方法。

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