Hyaluronic Acid - Gold Nanoparticle/Interferon a Complex for Targeted Treatment of Hepatitis C Virus Infection

机译：透明质酸-金纳米颗粒/干扰素复合物，用于靶向治疗丙型肝炎病毒感染

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HA-AuNP/IFNα complex was successfully developed for target-specific treatment of HCV infection. HA-AuNP/IFNα complex was effectively delivered to the liver by HA receptor mediated endocytosis promoting the IFNα-induced cytokine release. Furthermore, the HA-AuNP was thought to be effectively exploited to prepare a diverse protein complex for target-specific systemic treatment of various liver diseases.

机译：HA-AuNP /IFNα复合物已成功开发用于HCV感染的靶标特异性治疗。 HA-AuNP /IFNα复合物通过HA受体介导的内吞作用有效地传递到肝脏，从而促进IFNα诱导的细胞因子释放。此外，HA-AuNP被认为可有效地用于制备多种蛋白质复合物，用于各种肝病的靶标特异性全身治疗。

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《Society for Biomaterials annual meeting and exposition》|2013年|377|共1页
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Sei Kwang Hahn; Min-Young Lee; Jeong-A Yang; Ho Sang Jung; Wonhee Hur; Seung Kew Yoon;
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1. Hyaluronic acid-gold nanoparticle/interferon α complex for targeted treatment of hepatitis C virus infection [J] . Lee M.-Y., Yang J.-A., Jung H.S., ACS nano . 2012,第11期

机译：透明质酸-金纳米颗粒/干扰素α复合物靶向治疗丙型肝炎病毒感染
2. Target specific hyaluronic acid-interferon alpha conjugate for the treatment of hepatitis C virus infection. [J] . Yang JA, Park K, Jung H, Biomaterials . 2011,第33期

机译：靶向特异性透明质酸-干扰素α偶联物，用于治疗丙型肝炎病毒感染。
3. Hyaluronic acid co-functionalized gold nanoparticle complex for the targeted delivery of metformin in the treatment of liver cancer (HepG2 cells) [J] . Kumar C. Senthil, Raja M. D., Sundar D. Sathish, Carbohydrate Polymers: Scientific and Technological Aspects of Industrially Important Polysaccharides . 2015,第Null期

机译：透明质酸共官能化的金纳米颗粒复合物，可靶向递送二甲双胍，用于治疗肝癌（HepG2细胞）
4. Hyaluronic Acid - Gold Nanoparticle/Interferon a Complex for Targeted Treatment of Hepatitis C Virus Infection [C] . Sei Kwang Hahn, Min-Young Lee, Jeong-A Yang, Society for Biomaterials annual meeting and exposition . 2013

机译：透明质酸 - 金纳米粒子/干扰素是甲型肝炎病毒感染的靶向治疗的复合物
5. Evidence That Interferon Stimulates Production of Viral Double-stranded RNA During Hepatitis C Virus Infection [D] . Klepper, Arielle. 2015

机译：丙型肝炎病毒感染过程中干扰素刺激病毒双链RNA产生的证据
6. Effect of Treatment with Exogenous Interferon Polyinosinic Acid-Polycytidylic Acid or Polyinosinic Acid-Polycytidylic Acid-Poly-l-Lysine Complex on Encephalomyocarditis Virus Infections in Mice [O] . Gregg A. Olsen, Earl R. Kern, Lowell A. Glasgow, 1976

机译：外源性干扰素聚肌苷酸-聚胞苷酸或聚肌苷酸-聚胞苷酸-聚-1-赖氨酸复合物治疗对小鼠脑心肌炎病毒感染的影响
7. Effect of Treatment with Exogenous Interferon, Polyinosinic Acid-Polycytidylic Acid, or Polyinosinic Acid-Polycytidylic Acid-Poly-l-Lysine Complex on Encephalomyocarditis Virus Infections in Mice1 [O] . Olsen, Gregg A., Kern, Earl R., Glasgow, Lowell A., 1976

机译：外源性干扰素，聚肌苷酸-聚胞苷酸或聚肌苷酸-聚胞苷酸-聚-1-赖氨酸复合物治疗对小鼠脑心肌炎病毒感染的影响1

Hyaluronic Acid - Gold Nanoparticle/Interferon a Complex for Targeted Treatment of Hepatitis C Virus Infection

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