Study of cellular uptake and localization of metal oxide nanoparticles

摘要

Alexa 488 labeleling after APTES silanization constitute a suitable method to label metal oxide NPs allowing to study the uptake and localization by CLSM an Flow Cytometry. Raman Mycroscopy make possible to monitor the fate of unlabeled NPs, avoiding interferences due to the modification. The results obtained from the three techniques have been consistent.