Effects of peptides or charges bound to PEGylated nanoparticles on intracellular distribution and functionality of human primary reticuloendothelial cells

摘要

Our data suggest that the charge of nanoparticles mainly influences their uptake kinetics, whereas conjugated peptides alter the function of the cells. Our studies provide new insights into the effects of nanoparticle charge and coupled peptides on DC and MΦ functions.