Study of Conformational Change of Proteins Using Micromechanical Sensors

机译：利用微机械传感器研究蛋白质的构象变化

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The surface stress changes due to conformational change of the proteins upon interaction with specific analytes are promising as transducers of chemical information. We report here several biosensors due to conformational change of proteins by using microcantilevers. The proteins include glucose oxidase (GOx), organophosphorus hydrolyses (OPH), Calmodulin (CaM), and Horseradish peroxidase (HRP).

机译：与特定分析物相互作用后，由于蛋白质构象变化而引起的表面应力变化有望成为化学信息的转化者。由于使用微悬臂梁蛋白的构象变化，我们在这里报告了几种生物传感器。这些蛋白质包括葡萄糖氧化酶（GOx），有机磷水解酶（OPH），钙调蛋白（CaM）和辣根过氧化物酶（HRP）。

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《International Instrumentation Symposium》|2008年|P.91-95|共5页
会议地点 Pensacola BeachFL(US)
作者
Xin Yang; Koutilya; R. Buchapudi; Hongyan Gao; Xiaohe; Xu; Hai-Feng Ji;
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Instrumentation Systems and Automation Society(ISA);

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1. The ER protein folding sensor UDP-glucose glycoprotein–glucosyltransferase modifies substrates distant to local changes in glycoprotein conformation [J] . Sean C Taylor, Andrew D Ferguson, John J M Bergeron, Nature structural & molecular biology . 2004,第2期

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2. Effects of solute-matrix interaction on monitoring the conformational changes of immobilized proteins by surface plasmon resonance sensor [J] . Liang-Yu Chen, Ming-Chia Wu, Mao-Tsun Chou, Talanta: The International Journal of Pure and Applied Analytical Chemistry . 2005,第4期

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3. Measuring Adsorption of a Hydrophobic Probe with a Surface Plasmon Resonance Sensor to Monitor Conformational Changes in Immobilized Proteins [J] . Satoshi Yamaguchi, Teruhisa Mannen, Tamotsu Zako, Biotechnology Progress . 2003,第4期

机译：用表面等离子体共振传感器测量疏水探针的吸附，以监测固定蛋白的构象变化
4. Study of Conformational Change of Proteins Using Micromechanical Sensors [C] . Xin Yang, Koutilya, R. Buchapudi, International Instrumentation Symposium . 2008

机译：使用微机械传感器的蛋白质构象变化的研究
5. Novel surface energy sensor for detecting protein adsorption and subsequent conformation change. [D] . Clark, Alison Jane. 2005

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6. Amperometric Detection of Conformational Change of Proteins Using Immobilized-Liposome Sensor System [O] . Hyunjong Yu, Young Hwan Son, Hak-Jin Kim, 2018

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7. 1P-222 Study on light-induced conformational change and intermolecular interaction change of a blue light sensor protein PixD(Photobiology:Vision Photoreception, The 47th Annual Meeting of the Biophysical Society of Japan) [O] . Keisuke Tanaka, Yusuke Nakasone, Koji Okajima, 2009

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8. Studies on Pea Ribosomal Proteins: Conformational and Biological Activity Changes of Ribosomal Subunits Derived by NH4Cl-dissociation [R] . C. Y. Lin, L. S. Y. Chia, R. L. Travis 1973

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Study of Conformational Change of Proteins Using Micromechanical Sensors

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