Porous silicon with deposited iron oxide as vehicle for magnetically guided drug delivery

摘要

Due to the fact that both materials porous silicon as well as iron oxide nanoparticles are biocompatible and porous silicon can be functionalized easily to attach therapeutic nucleotides the aim is to create a cytocompatible arrangement to promote magnetically guided delivery into targeted cells. Furthermore porous silicon dissolves in body fluid dependent on the porosity which increases the possible applications. Within the frame of this work the field and temperature dependent magnetic properties of the nanocomposite have been investigated as well as its cytocompatibility according to the porous silicon morphology and the iron oxide particle size.