Biologically realistic simulation of a part of hippocampal CA3: Generation of testdata for the evaluation of spike detection algorithms

摘要

Biologically realistic simulations on the neuronal network level are frequently used in computational neuroscience in order to explain and understand biological brain functions. The presented simulation mimicks a tiny part of the CA3 region of the hippocampus. But new insights about the functionality of CA3 are not the ultimate goal in this case. Rather we want to show that sound extracellular potential data can be generated within a network close to reality. The data is used for the evaluation of spike detection methods.