Fluorescent chemosensors that signal carbohydrates in aqueous solution: a novel mechanism for signal transduction is required and found

摘要

Abstract: ylboronic acid (pK$-a$/ 8.8) displays decreased fluorescence in the boronate form compared with its boronic acid form, which we attribute to photoinduced electron transfer. When the boronic acid complexes to polyols such as fructose, the pK$- a$/ of the complex decreases; thus, the fluorimetrically determined pK$-a$/ of the 2-anthrylboronic acid:fructose borate ester is 5.9. These properties combined permit polyol complexation in water to be observed spectrofluorimetrically, which has not been reported previously. Fructose binds with a fluorimetrically determined K$-d$/ of 3.7 mM. !8