The role of salt bridge formation is very crucial in the conformation change of the proteins. Our earlier work had also confirmed the presence of salt bridge formations on the conformation change of the proteins in particular Calmodulin (CaM) protein. In the present study we perform the simulations of this protein at different temperatures and observe a crucial role of salt bride formations on the conformation changes observed. Parallel clusters are used to perform these simulations using the facilities of Inter University Accelerator Centre (IUAC), New Delhi, India. The present study is performed using computational facilities having namd package installed on the parallel clusters. Parallelization of this molecular dynamics (MD) package significantly helps to improve the computational time of the simulation.
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