A Fokker-Planck Approach for Modeling Integrated NanoBio Systems

摘要

Evaluation of microfluidic device and sensor designs using continuum modeling is a viable method, but becomes more complex if nanoscale or molecular level physics is to be included in the model. Recently, we have undertaken an effort to incorporate and understand nanoscale effects and how they impact continuum level simulations of microfluidics devices. This research focuses on how nanoscale physics can be incorporated into continuum level simulations using the Fokker-Planck Equation (FPE). The applications currently focus on shear influenced binding and biomolecular motors. The main challenge in these applications is the two way coupling of information generated in nanoscale simulations to the continuum level using a FPE approach.