摘要：
A 26-year-old female patient with excision of left breast fibroma received an Ⅳ infusion of lappaconite hydrobromide 8 mg in glucose and sodium chloride 500 ml once daily.No abnormality was found for the first time.About 20 minutes after Ⅳ infusion on the next day, the patient developed dry throat, slight dyspnea.Her respiratory rate was 25 times/min, heart rate was 55 beats/min and blood pressure was 70/55 mmHg.Lappaconite hydrobromide was discontinued immediately.She was given oxygen inhalation of 2 L/min, intravenous injection of adrenaline 0.5 mg, intravenous injection of adrenaline 10 mg, intramuscular injection of diphenhydramine 20 mg and IV infusion of dopamine 200 mg.After 5 minutes, the patient lost consciousness, had weak breathing, facial cyanosis and no pulsate.The electrocardiogram monitor displayed isoelectric line.The patient was treated with cardiopulmonary resuscitation, endotracheal intubation and ventilator support, chest compression, intravenous of epinephrine and infusion of hydrocor-tisone.The pathogenetic condition was getting worse progressively.The patient eventually died after 3 hours rescue.%1例26岁女性患者因左侧乳腺纤维瘤切除术后疼痛给予注射用氢溴酸高乌甲素8 mg入5%葡萄糖氯化钠500 ml静脉滴注,1次/d.首次用药未见异常.次日静脉滴注该药约20 min时,患者感觉喉部发干、轻微呼吸困难,呼吸25次/min,心率55次/min,血压 70/55 mmHg(1 mmHg=0.133 kPa).立即停用该药并吸氧(2 L/min),给予肾上腺素0.5 mg 静脉注射、地塞米松磷酸钠10 mg静脉注射、苯海拉明20 mg肌内注射、多巴胺200 mg静脉滴注.约5 min后患者出现呼之不应,呼吸微弱,面色发绀,大动脉搏动消失,心电监护示等电线.行心肺复苏、气管插管呼吸机辅助通气、持续胸外心脏按压,并静脉注射肾上腺素、静脉滴注氢化可的松等,但患者病情进行性加重.3 h后,患者因抢救无效死亡.
