扁桃体肿瘤
扁桃体肿瘤的相关文献在1989年到2022年内共计91篇,主要集中在肿瘤学、耳鼻咽喉科学、临床医学
等领域,其中期刊论文91篇、专利文献569039篇;相关期刊62种,包括中华病理学杂志、中国医学影像技术、现代肿瘤医学等;
扁桃体肿瘤的相关文献由271位作者贡献,包括徐震纲、吴钦苏、吴雪溪等。
扁桃体肿瘤—发文量
专利文献>
论文:569039篇
占比:99.98%
总计:569130篇
扁桃体肿瘤
-研究学者
- 徐震纲
- 吴钦苏
- 吴雪溪
- 周晓军
- 唐平章
- 布洁
- 张玲
- 祁永发
- 郭汝元
- 陶兴罡
- 马恒辉
- Chen Shuyuan
- Hai-Miao Xu
- Li-Ming Sheng
- Li-Zhen Zhang
- Wei Jia
- Xie Jianlan
- Yuan Zhu
- Zhang Xiaojing
- Zhou Xiaoge
- 于燕霞
- 仇玲妹
- 付文元
- 付淑云
- 任何贤
- 任健
- 任淑惠
- 何发尧
- 何小慧
- 何惠华
- 何文霞
- 何永萍
- 何美文
- 侯世东
- 侯卫华
- 修元德
- 兰海涛
- 兰胜明
- 兰胜民
- 冯强
- 冯照远
- 刘保安
- 刘克拉
- 刘华婵
- 刘孟加
- 刘学娟
- 刘建辉
- 刘敏
- 刘文胜
- 刘汉忠
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聂洪婷;
翟长文;
林岚
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摘要:
患者女性,46岁。因咽部异物感2周余入院,近期出现关节酸痛,影像学CT示:左侧扁桃体软组织肿块影(图1)。查体:面部皮下呈斑点状凸起;左侧扁桃体上极见一溃疡,Ⅱ度肿大。实验室检查血清肿瘤学相关指标未见异常,未行EB病毒血清学检测,HIV检测呈阳性。病理检查,眼观:完整扁桃体1块,2.5 cm×2.3 cm×1.4 cm,表面见溃疡,切面灰白色,质实。
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曹丽红;
赵雪;
李尧;
王建玲
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摘要:
目的 探讨原发扁桃体非霍奇金淋巴瘤(NHL)的临床病理特征、诊断治疗及预后.方法 回顾性分析天津医科大学总医院2007年1月—2014年1月收治的经病理确诊的21例原发扁桃体NHL的临床资料,总结其临床病理特点、分期及预后.结果 21例原发扁桃体NHL占同期行扁桃体手术病理患者的2.6%(21/807).其中男13例,女8例,平均发病年龄(50.8±12.9)岁.单侧发病19例(90.5%).病理学诊断源于B细胞20例(95.2%),其中弥漫大B细胞型13例(61.9%),滤泡性4例(19.0%),套细胞型3例(14.3%);源于T细胞1例(4.8%).按照Ann-Arbor标准分期Ⅰ~Ⅱ期18例,5年生存率为71.4%;Ⅲ~Ⅳ期3例,5年生存率为0.结论 原发扁桃体NHL较为罕见,早期患者预后较好,重视本病的早期诊断、早期治疗是提高5年生存率的关键.
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Zhang Xiaojing;
Zhou Xiaoge;
Wei Jia;
Xie Jianlan;
Chen Shuyuan
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摘要:
Objective To investigate the clinicopathological features of long?term tumor?free survival in patients with untreated primary diffuse large B?cell lymphoma (DLBCL) of the tonsil. Methods The study included 80 consultation cases of primary tonsillar DLBCL from April 2006 to July 2017 in the Department of Pathology, Beijing Friendship Hospital, Capital Medical University. The patients were divided into two groups: experimental groups of 10 untreated patients with long?term tumor?free survival, and 70 patients who had been treated (control group). The clinical data, histopathological features, immunohistochemical staining, and molecular biology test results of the patients were analyzed retrospectively. Results Patients who had long?term tumor?free survival with untreated primary diffuse large B?cell lymphoma had the disease mostly confined to the tonsil. Biopsy showed that the tonsil structure was only partially effaced and the lesions were relatively "fresh". EBER and FISH test for t (14;18) results were negative. Gene rearrangement detection showed monoclonality. There was statistically significant difference between the age, bcl?2 expression, CMYC protein expression and co?expression of CMYC and bcl?2 between the untreated group and the treated group(P0.05);The median overall survival of the untreated group and treated group was 81 months and 20 months, respectively, and the difference was not statistically significant (P>0.05).In patients younger than 40 years of age, the untreated group had a statistically significant difference in primary site and CMYC protein expression compared with the treated group (P0.05);未放化疗组和已治疗组中位总生存期分别为81及20个月,差异无统计学意义(P>0.05).在年龄0.05).结论 未放化疗而长期无瘤生存的原发扁桃体DLBCL具有相对独特的临床和病理学特征.生存分析结果显示未放化疗组可长期无瘤生存,可以使患者免受放疗和化疗带来的副作用.
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侯卫华;
韦萍;
谢建兰;
郑媛媛;
张燕林;
周小鸽
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摘要:
Objective To investigate clinicopathological features and prognosis of tonsillar mantle cell lymphoma(TMCL). Methods Clinical data of 25 patients with TMCL at Beijing Friendship Hospital, Capital Medical University from 2002 to 2016 were included. All the cases were reviewed microscopically. Various immunohistochemical stains were performed using the MaxVision two-step method. IgH/CCND1 gene fusion was detected by fluorescent in situ hybridization(FISH). Additionally, randomly selected 40 cases of non-tonsil MCL of the same period were compared. Results Among all mantle cell lymphomas (MCL),TMCL accounted for 5.6%(25/449). The median age of the patients was 60 years(range:44-82 years)with a M:F ratio of 5.3 to 1.0. The main symptoms were sore throat and foreign body sensation and patients usually presented with enlargement or mass of tonsil. At the early stage of the disease,18 cases (72.0%)were clinically misdiagnosed as tonsillitis. Lymph node involvement was present in 76.0%(19/25)of the patients. There were 4 cases(16.0%)with current splenic involvement,11 cases(44.0%) with pharyngeal focal recidivism, and 3 cases(12.0%)with involvement of other non-lymphoid organs. Morphologically, tonsillar architectures were effaced at various degrees. Eighteen MCL cases showed classical type and 7 cases were blastoid variant. All tumors were positive for CD20 and cyclin D1. 92.0%(23/25)tumors showed weakly positive or positive expression for CD5. FISH test that IgH/CCND1 gene fusion was positive in two CD5 negative classical cases. 18 patients(72.0%)had a median follow-up time of 26 months(range:6-81 months). The difference of survival rate between stage Ⅰ-Ⅱ and stage Ⅲ-Ⅳpatients was not statistically significant(P>0.05). Compared with NTMCL,TMCL was found to have higher proportion of stage Ⅰ-Ⅱ disease(χ2=12.789,P0.05).与NTMCL比较,TMCL患者就诊时Ⅰ~Ⅱ期比例更高(χ2=12.789,P<0.01),非淋巴器官侵犯比例更低(χ2=8.125,P<0.01),预后更好(χ2=4.351,P=0.037).结论 TMCL发病率低,临床易诊为扁桃体炎,就诊时Ⅰ~Ⅱ期患者比例高,较NTMCL预后更好.
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魏淑飞;
曹清;
徐晓;
汪亮亮;
黄文勇;
李婷
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摘要:
目的 探讨纤维母细胞性网状细胞肿瘤(fibroblastic reticular cell tumor,FRCT)的临床病理学特点、诊断及鉴别诊断.方法 回顾性分析1例扁桃体FRCT的临床病理学特征并复习相关文献.结果 患者行右侧扁桃体肿物活检,镜下见扁桃体正常结构被破坏,肿瘤细胞增生,肿瘤细胞梭形、多边形、圆形或卵圆形,呈束状、漩涡状或席纹状排列,肿瘤细胞间可见多量散在的嗜酸性粒细胞和中性粒细胞,肿瘤细胞边界不清,细胞核呈空泡状,核膜光滑或不规则,细胞核有轻~中度异型性,可见核仁,核分裂易见(> 10/50 HPF).免疫表型:肿瘤细胞Kp-1、vimentin均阳性,CK(AE1/AE3)和SMA均灶状阳性,S-100蛋白弱阳性,CD20、ALK、CD3、CD23、CD21、CD35、CD34、desmin、p63、CK5/6和CKL均阴性,EBER原位杂交检测阴性.结论 FRCT临床较少见,发生于扁桃体者更为少见,诊断主要依赖病理学及免疫表型.