women

摘要： Polycystic ovary syndrome(PCOS)often coexists with a wide spectrum of dysglycemic conditions,ranging from impaired glucose tolerance to type 2 diabetes mellitus(T2D),which occur to a greater extent compared to healthy body mass index-matched women.This concurrence of disorders is mainly attributed to common pathogenetic pathways linking the two entities,such as insulin resistance.However,due to methodological flaws in the available studies and the multifaceted nature of the syndrome,there has been substantial controversy as to the exact association between T2D and PCOS which has not yet been elucidated.The aim of this review is to present the best available evidence regarding the epidemiology of dysglycemia in PCOS,the unique pathophysiological mechanisms underlying the progression of dysglycemia,the most appropriate methods for assessing glycemic status and the risk factors for T2D development in this population,as well as T2D risk after transition to menopause.Proposals for application of a holistic approach to enable optimal management of T2D risk in PCOS are also provided.Specifically,adoption of a healthy lifestyle with adherence to improved dietary patterns,such the Mediterranean diet,avoidance of consumption of endocrine-disrupting foods and beverages,regular exercise,and the effect of certain medications,such as metformin and glucagon-like peptide 1 receptor agonists,are discussed.Furthermore,the maintenance of a healthy weight is highlighted as a key factor in achievement of a significant reduction of T2D risk in women with PCOS.

摘要： Menopause is the last step in the reproductive history of a woman. The ovaries stop producing hormones and the body reacts by lowering its functions, including the cognitive one. Phytoestrogens are plant products with the estrogen-like activity which are able to mimic many of estrogen’s functions. The aim of the present experiment was to study the effects of 30 days of regular consumption of soy-enriched bread containing a known amount of phytoestrogens (genistein and daidzein) in climacteric or menopausal women. Thirty women at different stages of menopause (climacteric, within 5 years of menopause, more than 5 years of menopause) were asked to include 200 g/die of bread containing 40 mg of phytoestrogens in their diet. The effect of the regular consumption of this bread on common menopausal symptoms and cognitive parameters was determined before and after 30 days through questionnaires and experimental tests. Phytoestrogens were measured in the urine. Twenty-five women completed the study. Independence of the menopause stage, there was a significant increase of phytoestrogens in the urine and a decrease of the classical symptoms (i.e., hot flushes). Moreover, the women showed a significant improvement in attentional performance tests, the quality of life index and pain intensity. Phytoestrogens would be an important supplement in aging women due to their ability to induce estrogen-like effects without the potential side effects of estrogens. Their presence in soy-enriched bread, a food commonly present in meals, avoids consideration of their consumption as a drug.

摘要： BACKGROUND Unexplained infertility(UI)is usually used for any heterosexual couple who failed to have a successful clinical pregnancy without identifying clear causes after they undergo all standard fertility tests.Evidence shows that leptin is one of the most accurate biomarkers for UI.Nevertheless,conflicting results regarding leptin levels in women with UI have been reported.AIM To find the serum leptin levels in women with UI.METHODS All studies written in English and conducted before April 30,2021 from PubMed/MEDLINE,Embase,Cochrane Central Register of Controlled Trials,ClinicalTrials.gov,Google Scholar,OpenGrey,OATD,and the infertility conference abstract were included.Studies were found eligible if they provided the mean and standard deviation of leptin for the case group and control group.The quality assessment of individual studies was evaluated using the Joanna Briggs Institute Quality Assessment Tool.Data synthesis and statistical analysis were done using STATA software version 16.RESULTS A total of 378 studies were reviewed,and just six studies that fulfilled the eligibility criteria were included in this meta-analysis.The pooled result showed that leptin levels were significantly higher in women with UI compared to fertile women,with a standardized mean difference of 0.97(95%confidence interval:-0.49-2.43).However,heterogeneity across studies was highly significant(P<0.00001;I2=98.8%).CONCLUSION The results of this study suggest that leptin levels are elevated in women with UI compared with fertile women;hence,leptin could be a potential biomarker for UI in women,and it may be useful for identifying women with a high risk of infertility.

摘要： Objective:To summarize medicinal plants used in the treatment of couple fertility disorders.Methods:An ethnopharmacological survey was conducted with 30 traditional healers from some localities of Skikda region in eastern Algeria.A standard questionnaire was used in the interview which focused mainly:the treated fertility disorders,the used medicinal plants species,parts used,and preparation methods.The relative frequency of citation and percentages of infertility troubles were calculated and analyzed.Results:The most important treated disorders in men were dysfunction of libido(44.22%),low sperm concentration and motility(25.33%),low semen volume(17.67%)and prostate disorders(5.66%).Women were treated mainly for menstruation disorders(35.32%),breast problems(29.53%)and sexual asthenia(25.82%).The survey identified 28 plant species belonging to 15 families,used by different ethnic groups,particularly women(58.00%),to address different fertility disorders.Three plant families were largely used viz Lamiaceae,Asteraceae,and Apiaceae.In term of relative frequency citation,ten dominated plant species were:Zingiber officinalis L.(0.96),Nigella sativa L.(0.83),Lepidium sativum L.(0.80),Capsicum annuum L.(0.60),Cuminum cyminum L.(0.56),Origanum vulgare L.(0.55),Allium sativum L.(0.50),Petroselinum sativum L.(0.43),Salvia officinalis L.(0.42),and Foeniculum vulgare L.(0.40).A number of investigated plants were scientifically confirmed by phytochemical and pharmacological studies to have one or more significant effects on couple fertility.However,much controversy was found in literature concerning the efficacy of some cited plants.Conclusions:The study highlights the important use of medicinal plants in management of couple infertility in eastern Algeria.More experimental studies are recommended to confirm or to refute these traditional uses and to ascertain the safety of these medicinal plants to consumers.

摘要： Introduction: The incidence of bladder cancer in women has steadily increased in recent years. The objective of our work is to study the epidemiological profile of bladder cancer in women in our population and the factors favoring its occurrence. Methods: This is a retrospective study carried out at the Mohamed Center VI for cancer treatment, involving 27 women during a two-year period from January 2019 to December 2020. We studied the epidemiological characteristics in these patients, the risk factors and the revealing symptoms. Results: The average age of patients was 67.5 years old and 66.66% of the patients were over 65 years old. One patient had in her antecedents a tumor of the upper excretory tract and 2 patients had an associated renal tumor. The notion of smoking was found in 3 patients. The time to treatment was less than 6 months in 44.4% of cases, between 6 and 12 months in 18.5% of cases, and more than a year in 37% of cases. The symptoms were marked by hematuria in 96.3% of cases, and irritative disorders in 81.4% of cases. In our series;the tumor was unifocal in 77.77% of the cases, and multifocal in the remainder of the cases. Urethrohydronephrosis was found in 74% of cases. Histologically, it was an urothelial carcinoma in 81.48% of cases. The tumor was locally advanced in 11.11% of cases, and metastatic in 11.11% of cases. Lymph node involvement was found in 33.33% of cases. 48.1% of cases underwent surgery. The operative procedure consisted of a partial cystectomy in 46.1% of cases, and only 18.5% was suitable for trimodal treatment. Conclusion: Few studies have addressed the epidemiology of bladder cancer in women due to the low incidence, but it is currently increasing steadily in recent years. These modifications are explained by the change in social habits in women.

摘要： The study employed the triangulation approach to investigate the impact of climate variability on selected socioeconomic indicators, particularly food production, health and education, and how much climate variability and its impact on those indicators was realized and understood among the women living in Jambiani community in Zanzibar. The study used the explanatory, sequential mixed method to collect, datasets related to Jambiani communities (i.e. from the women in Kibigija village), other climate data acquired from Tanzania Meteorological Authority (TMA), Ministries of Agriculture and Health and Southern District in Zanzibar. The results obtained from the analysis of both anecdotal (interview, questionnaire among others) data shows that climate variability was imminent in Jambiani communities between 2010 and 2015 and had a negative impact on food production, health and education. Further results revealed that women working in informal sectors are more vulnerable to climate impacts than women working in formal sectors due to less knowledge and techniques to mitigate/cope with climate variability impacts. Conclusively the study has shown that climate variability affects more women with less awareness of what is happening and how to cope with it, thus the study calls for new research work and increasing the awareness on the impacts of climate on human basic needs.

摘要： Introduction: When it comes to family planning, requirements and preferences vary among couples. Because of their mixed effectiveness, traditional contraceptive methods are often associated and accounted as unmet needs. However, interest in these methods is growing significantly. Nevertheless, knowledge of the reasons for the decision and using traditional contraceptive methods remains limited. The purpose of this study was to identify the preferences and motivations of women who use traditional contraceptive methods to avoid pregnancy in Sub-Saharan Africa. Method: A literature search was conducted in three electronic databases (PubMed/Biomed Central/Medline, Embase, CINAHL). Two independent individuals selected the eligible quantitative, qualitative, and mixed studies published between 2011 and 2020. We conducted a narrative synthesis to organize and group preferences and motivations that facilitate traditional contraceptive methods use. Results: Abstinence, withdrawal, breastfeeding, rhythm method were the main preferences to contraceptive planning methods identified. Factors influencing the use of traditional contraceptive methods were the lack of knowledge, the side effects, the bad experience with the modern contraceptive methods, spousal communication around family planning, the husband’s opposition to modern methods, availability, accessibility, and the absence of side effects as well as the character of the traditional methods, the fact of living in an urban environment as well as the age beyond 30 years. Conclusion: This review identified preferences and motivations for using traditional contraceptive methods. These findings could be considered in different family planning programs to understand their role and help to estimate the contraceptive prevalence better.

摘要： Background:Meeting the contraceptive needs of women of reproductive age is beneficial for the health of women and children,and the economic and social empowerment of women.Higher rates of contraceptive coverage have been linked to the availability of a more diverse range of contraceptive methods.We present estimates of the contraceptive prevalence rate(CPR),modern contraceptive prevalence rate(mCPR),demand satisfied,and the method of contraception used for both partnered and unpartnered women for 5-year age groups in 204 countries and territories between 1970 and 2019.

摘要： Objectives:To explore the clinical manifestations and pathological features in the biopsy of ovarian Sertoli-Leydig cell tumor,as well as to improve the clinical understanding of the disease.Methods:A case of pregnancy and childbirth after Sertoli-Leydig cell tumor resection was retrospectively analyzed.The patients’clinical data were collected,including the clinical manifestations,postoperative biopsy results,auxiliary examination results,immunohistochemical results,treatment,and prognosis of the patient.Results:(1)SLCT occurred unilaterally;(2)according to the International Federation of Obstetrics and Gynecology(FIGO),the clinical staging was stage IA;according to the pathological classification of malignant tumors,it was gradeⅡ(moderately differentiated);(3)a healthy female live baby was delivered.Conclusion:Such tumors are rare low-grade malignancies and are even rarer in pregnancy.An increase in preoperative testosterone levels with positive ultrasonography results can be used to assist diagnosis;however,postoperative biopsy pathology remains the“gold standard”for the diagnosis of SLCTs.The definite diagnosis of SLCTs is of great significance for surgical planning and prognostic evaluation.

摘要： It is believed that the true meaning of Democracy could be found only when the rule-makers of the nation are chosen by the politically aware people.According to Aristotle,democracy is the worst form of government,because it is the rule of the illiterate and unaware people.It implies that for the successful running of a democratic set-up,the spread of education and consciousness are the basic crucial requirements.In this regard we may remember the observations of Lord Bryce,that the gift of the suffrage creates the will to use it,and the gift of knowledge creates the capacity to use this right in a proper way.Taking into account this view,the issue of the participation of women into politics has become imperative in the present global situation.This issue is intricately related to the increasing consciousness about eradicating inequalities,especially gender inequality,to cater to equal opportunities regarding sharing the resources and in the policy-making processes,which are the demands of the day.Within this paper I intend to study into the reality of women’s participation and the probable factors that withheld them from being actively involved into politics.