Axis

摘要： 由于FPGA片内存储资源有限,扩展外部存储空间是必要的,然而众多存储芯片总线结构复杂,控制繁琐.为此,本文以赛灵思的FPGA为平台,设计一种以常用而快捷的axi_stream的形式访问SDRAM的接口.

摘要： The intimate connection and the strict mutual cooperation between the gut and the liver realizes a functional entity called gut-liver axis.The integrity of intestinal barrier is crucial for the maintenance of liver homeostasis.In this mutual relationship,the liver acts as a second firewall towards potentially harmful substances translocated from the gut,and is,in turn,is implicated in the regulation of the barrier.Increasing evidence has highlighted the relevance of increased intestinal permeability and consequent bacterial translocation in the development of liver damage.In particular,in patients with non-alcoholic fatty liver disease recent hypotheses are considering intestinal permeability impairment,diet and gut dysbiosis as the primary pathogenic trigger.In advanced liver disease,intestinal permeability is enhanced by portal hypertension.The clinical consequence is an increased bacterial translocation that further worsens liver damage.Furthermore,this pathogenic mechanism is implicated in most of liver cirrhosis complications,such as spontaneous bacterial peritonitis,hepatorenal syndrome,portal vein thrombosis,hepatic encephalopathy,and hepatocellular carcinoma.After liver transplantation,the decrease in portal pressure should determine beneficial effects on the gut-liver axis,although are incompletely understood data on the modifications of the intestinal permeability and gut microbiota composition are still lacking.How the modulation of the intestinal permeability could prevent the initiation and progression of liver disease is still an uncovered area,which deserves further attention.

摘要： Despite their high prevalence, lack of understanding of the exact pathophysiology of the functional gastrointestinal disorders has restricted us to symptomatic diagnostic tools and therapies. Complex mechanisms underlying the disturbances in the bidirectional communication between the gastrointestinal tract and the brain have a vital role in the pathogenesis and are key to our understanding of the disease phenomenon. Although we have come a long way in our understanding of these complex disorders with the help of studies on animals especially rodents, there need to be more studies in humans, especially to identify the therapeutic targets. This review study looks at the anatomical features of the gut-brain axis in order to discuss the different factors and underlying molecular mechanisms that may have a role in the pathogenesis of functional gastrointestinal disorders. These molecules and their receptors can be targeted in future for further studies and possible therapeutic interventions. The article also discusses the potential role of artificial intelligence and machine learning and its possible role in our understanding of these scientifically challenging disorders.

摘要： BACKGROUND In non-alcoholic fatty liver disease(NAFLD), a high-fat or high-fructose diet increases intestinal permeability and promotes derangement of the gut-liver axis.We hypothesize that, diet could be able to modulate intestinal permeability in patients with NAFLD.AIM To detect diet-induced modification of intestinal permeability in patients with NAFLD undergoing a Mediterranean diet or a low-fat diet.METHODS The current study was a dietary intervention for non-diabetic, patients with biopsy-verified NAFLD and increased transaminases. A crossover design was employed: participants underwent 16 weeks of Mediterranean diet, 16 wk of free wash-out, and 16 weeks of low-fat diet. Both diets were hypocaloric and no consumption of supplements was allowed. All patients were followed bimonthly by a dietitian. Evaluations of clinical and metabolic parameters were completed at baseline and at the end of each dietary period. Intestinal permeability was assessed by chromium-51 ethylene diamine tetraacetate excretion testing(51 CrEDTA).RESULTS Twenty Caucasian patients, 90% male, median age 43 years, body mass index(BMI) 30.9, with biopsy-verified NAFLD were enrolled. At the end of 16 weeks of a Mediterranean diet, a significant reduction in mean body weight(-5.3 ± 4.1 kg,P = 0.003), mean waist circumference(-7.9 ± 4.9 cm, P = 0.001), and mean transaminase levels [alanine aminotransferase(ALT)-28.3 ± 11.9 IU/L, P =0.0001; aspartate aminotransferase(AST)-6.4 ± 56.3 IU/L, P = 0.01] were observed. These benefits were maintained after 16 wk of wash-out and also after16 wk of low-fat diet, without further improvements. Fourteen of the 20 patients had intestinal permeability alteration at baseline(mean percentage retention of51 Cr-EDTA = 5.4%), but no significant changes in intestinal permeability were observed at the end of the 16 wk of the Mediterranean diet or 16 wk of the low-fat diet.CONCLUSION Mediterranean diet is an effective strategy for treating overweight, visceral obesity and serum transaminase in patients with NAFLD. If the Mediterranean diet can improve intestinal permeability in patients with NAFLD, it deserves further investigation.

摘要： In this study, a total of 115,246 ground motions recorded during earthquakes of Moment magnitudes ranging from M_w 5.0 to M_w 9.0 are analyzed statistically. A total of 21 ground motion parameters characterising the recorded acceleration time histories are used in the analysis. Classification of these parameters through statistical correlation is reported and a parameter called "distance from zero-amplitude axis," or d_(Z-A), is formulated in the principal component space. The ability for d_(Z-A) to rate the damage potentials of strong motion records is evaluated through correlation of d_(Z-A) with Japan Meteorological Agency(JMA) instrumental seismic intensities. This parameter can be used to rate damage potential of any strong motion record irrespective of the magnitude and location of the earthquake. It can also be used in selecting ground motion records of appropriate damage potential in seismic design and probabilistic analysis.

摘要： L-glutamic acid (glutamate-Glu) serves as one form with very strong stimulatory neurotransmitter (near aspartic, kainic, alpha-amino-3-hydroxy-5-me- thyl-4-izoxazole propionic acid (AMPA), chinolic and L-homocysteinic acid, glycine and D-serine) at the majority of neural excitatory synapse in the mammals and nonmammals central, sympathetic nervous system (CNS and SNS, respectively) and in different peripheral tissues and organ. It mediates interactions via stimulation a variety ionotropic N-methyl-D-As- partate (NMDA), AMPA and kainate receptors (ligand gated calcium channels) and III groups of the metabotropic glutamate receptors (mGluR1-8) family members (G-protein coupled receptors). It is good known different neuromodula-tion/interaction between Glu and norepinephrine (NE), dopamine (DA), gamma-amino-butyric acid (GABA), oxytocin/vasopressin (Oxy/AVP) and steroid receptors during stress in the central nervous system. In this review we describe the molecular structure of these glutamatergic receptors and discuss they neuropharmacology and clinical use probability of their antagonist, in stress particularly. On the other hand it was interesting if Glu can increase catecholamine (CA) release from motivational structures as stressoric factor in hypothalamo-pituitary adrenal axis (HPA) in the stress inducing processes. Our findings show that Glu more influences the brain’s motivational structure, which may indicate its contribution to the stress response by direct modulating the amount of catecholamine released.

摘要： Wind energy witnessed tremendous growth in the past decade and emerged as the most sought renewable energy source after solar energy. Though the Horizontal Axis Wind Turbines (HAWT) is preferred for multi-megawatt power generation, Vertical Axis Wind Turbines (VAWT) is as competitive as HAWT. The current study aims to summarize the development of VAWT, in particular, Darrieus turbine from the past to the project that is underway. The reason for the technical challenges and past failures are discussed. Various configurations of VAWT have been assessed in terms of reliability, components and low wind speed performance. Innovative concepts and the feasibility to scale up for megawatt electricity generation, especially in offshore environments are investigated. This paper is a modest attempt to highlight the state-of-the-art information on the ongoing developments focusing on decentralized power generation. This review is envisioned as an information hub for the major developments in VAWT and its technical advancements so far.

摘要： BACKGROUND Non-alcoholic fatty liver disease(NAFLD)has become a major cause of chronic liver disease.The Chinese herbal medicine(CHM)Dachaihu decoction(DCHD)has been proved to treat NAFLD with good efficacy in previous studies.Based on the TCM principle of formula formation,we divided DCHD into soothing liver part,invigorating spleen part,and dredging intestine part.Marshall officially proposed the concept of“intestinal-hepatic axis”,which systematically explains the interactions between the intestine and liver.We hypothesized that the effect of CHM on NAFLD is achieved by regulating the liver and intestine.Thus,we aimed to investigate the possible effect of a CHM formula on NAFLD in a rat model.AIM To investigate the effects of a CHM formula(a decoction of Chinese thorowax root,scutellaria root,and white peony root)on NAFLD and its regulatory effect on the“intestinal-liver”axis.METHODS Sixty rats were randomly divided into control,model,pioglitazone hydrochloride(PH),and CHM(a decoction of Chinese thorowax root,scutellaria root,and white peony root)groups.An NAFLD rat model was established using a high-fat highfructose diet for 16 wk.From the 13th week,rats were administered with PH or a decoction of Chinese thorowax,scutellaria,and white peony root(CHM group)for 4 wk.Rats in the control group and model group were administered with an equal volume of distilled water.At the end of the study,blood was collected via the abdominal aorta.Liver tissues were harvested and any morphological changes were observed by hematoxylin-eosin(HE)staining,Oil red O staining,and Masson staining.In addition,blood lipids,liver function markers,and triglyceride(TG)in liver tissues were analyzed.The levels of transforming growth factor-β1(TGF-β1),tumor necrosis factor-α(TNF-α),Toll-like receptor-4(TLR4),and nuclear factor-kappa B(NF-кB)in liver tissues and secreted immunoglobulin A(sIgA)in intestinal tissues were analyzed by ELISA,and protein and mRNA expression of occludin and zonula occludens-1(ZO-1)in the intestine were measured using Western blot and reverse transcriptionquantitative polymerase chain reaction,respectively.The endotoxin level in plasma was detected by endpoint chromogenic assay.RESULTS Compared to the normal control group,the liver coefficient,serum TG,total cholesterol(TC),low density lipoprotein(LDL),aspartate aminotransferase(AST),and alanine aminotransferase(ALT),blood glucose,plasma endotoxin,and the levels of TG,TNF-α,TGF-β,NF-kB,and TLR4 in liver tissues increased significantly in the model group,while serum high density lipoprotein(HDL),intestinal sIgA,and protein and mRNA expression of occludin and ZO-1 decreased significantly in the model group(P<0.01).PH and CHM attenuated the elevated liver coefficient,serum TG,TC,LDL,AST,and ALT,blood glucose,plasma endotoxin,and the levels of TG,TNF-α,TGF-β,NF-kB,and TLR4 in liver tissues and increased serum HDL levels compared to the model group(P<0.01).Intestinal sIgA and the protein and mRNA expression of intestinal occludin and ZO-1 were significantly increased in the PH group compared to the model and CHM groups(P<0.01).CONCLUSION The decoction of Chinese thorowax root,scutellaria root,and white peony root is beneficial in regulating lipid metabolism and liver function,which indicates that it has a good effect on the liver.To a certain extent,this CHM formula can affect both the liver and intestine,while its effect on the liver is superior to that on the intestine.

摘要： 专利申请号:US201816027113申请日:2018.07.03公开号:US2018328131A1公开日:2018.11.15申请人:PETROMAC IP LTD;A logging tool assembly comprises an elongate sensor assembly, a plurality of sensor transportation apparatuses for transporting the elongate sensor assembly through a wellbore, and an orientation structure. The sensor transportation apparatuses are spaced apart along the elongate sensor assembly. Each sensor transportation apparatus comprises an engagement structure to connect the sensor transportation apparatus to the elongate sensor assembly and prevent relative rotation between the sensor transportation apparatus and the elongate sensor assembly, and one or more pairs of wheels arranged to rotate on an axis of rotation substantially perpendicular to a longitudinal axis of the elongate sensor assembly.

摘要： Despite the lack of precise mechanisms of action, a growing number of studies suggests that gut microbiota is involved in a great number of physiological functions of the human organism. In fact, the composition and the relations of intestinal microbial populations play a role, either directly or indirectly, to both the onset and development of various pathologies. In particular, the gastrointestinal tract and nervous system are closely connected by the so-called gut–brain axis, a complex bidirectional system in which the central and enteric nervous system interact with each other, also engaging endocrine, immune and neuronal circuits. This allows us to put forward new working hypotheses on the origin of some multifactorial diseases: from eating to neuropsychiatric disorders (such as autism spectrum disorders and depression) up to diabetes and tumors (such as colorectal cancer). This scenario reinforces the idea that the microbiota and its composition represent a factor, which is no longer negligible, not only in preserving what we call “health” but also in defining and thus determining it. Therefore, we propose to consider the gut-brain axis as the focus of new scientific and clinical investigation as long as the locus of possible systemic therapeutic interventions.

摘要： 以 J2EE 和 .NET 为平台的 WebService 客户端1在 AXIS 下，由于 SOAP 的 RPC/Encoded 编码模式会引起 WebService 互操作性问题。本文根据 AXIS 的系统结构特征并对其源码进行改进，提出了一种根据SOAP消息格式的自适应解决方案。该设计通过 J2EE和.NET下以数组和结构等复杂数据结构为例的测试，实现了 J2EE 和.NET 的 WebServer 客户端在 AXIS 上的互操作。

摘要： 以 J2EE 和 .NET 为平台的 WebService 客户端1在 AXIS 下，由于 SOAP 的 RPC/Encoded 编码模式会引起 WebService 互操作性问题。本文根据 AXIS 的系统结构特征并对其源码进行改进，提出了一种根据SOAP消息格式的自适应解决方案。该设计通过 J2EE和.NET下以数组和结构等复杂数据结构为例的测试，实现了 J2EE 和.NET 的 WebServer 客户端在 AXIS 上的互操作。

摘要： 以 J2EE 和 .NET 为平台的 WebService 客户端1在 AXIS 下，由于 SOAP 的 RPC/Encoded 编码模式会引起 WebService 互操作性问题。本文根据 AXIS 的系统结构特征并对其源码进行改进，提出了一种根据SOAP消息格式的自适应解决方案。该设计通过 J2EE和.NET下以数组和结构等复杂数据结构为例的测试，实现了 J2EE 和.NET 的 WebServer 客户端在 AXIS 上的互操作。

摘要： 以 J2EE 和 .NET 为平台的 WebService 客户端1在 AXIS 下，由于 SOAP 的 RPC/Encoded 编码模式会引起 WebService 互操作性问题。本文根据 AXIS 的系统结构特征并对其源码进行改进，提出了一种根据SOAP消息格式的自适应解决方案。该设计通过 J2EE和.NET下以数组和结构等复杂数据结构为例的测试，实现了 J2EE 和.NET 的 WebServer 客户端在 AXIS 上的互操作。

摘要： 以 J2EE 和 .NET 为平台的 WebService 客户端1在 AXIS 下，由于 SOAP 的 RPC/Encoded 编码模式会引起 WebService 互操作性问题。本文根据 AXIS 的系统结构特征并对其源码进行改进，提出了一种根据SOAP消息格式的自适应解决方案。该设计通过 J2EE和.NET下以数组和结构等复杂数据结构为例的测试，实现了 J2EE 和.NET 的 WebServer 客户端在 AXIS 上的互操作。

摘要： 以 J2EE 和 .NET 为平台的 WebService 客户端1在 AXIS 下，由于 SOAP 的 RPC/Encoded 编码模式会引起 WebService 互操作性问题。本文根据 AXIS 的系统结构特征并对其源码进行改进，提出了一种根据SOAP消息格式的自适应解决方案。该设计通过 J2EE和.NET下以数组和结构等复杂数据结构为例的测试，实现了 J2EE 和.NET 的 WebServer 客户端在 AXIS 上的互操作。

摘要： 本发明公开了一种基于AXI协议的广播传输方法、系统及介质，包括：通过请求缓冲模块，基于AXI协议接收Master节点发送的广播传输请求，以及与广播传输请求对应的广播位域，并将广播传输请求以及广播位域传输至分发模块；通过分发模块，根据广播位域将广播传输请求发送至至少一个目标Slave节点；通过响应反馈模块，接收各目标Slave节点发送的响应数据，并将各目标Slave节点对应的响应数据，传输至Master节点。本发明实施例的技术方案可以提高AXI总线的广播传输性能，降低广播传输系统的复杂度，提高广播传输过程的灵活性。

摘要： 本申请公开了一种AXI总线通信方法、装置、设备和介质，涉及集成电路技术领域。包括：发起端向目标端发起请求；所述目标端将所述请求中的数据信息存储至请求数据存储队列；所述目标端根据所述数据信息计算得到第一时间，并将所述数据信息从所述请求数据存储队列存入请求响应队列；所述目标端响应于检测到等待第二时间后，所述目标端根据所述请求响应队列读取所述数据信息，将所述数据信息发送至所述发起端；发起端接收到所述数据信息，对所述数据信息进行处理，将处理后的数据信息返回至所述目标端。本申请将数据传输分为多个阶段，能够模拟总线的传输延时性、端口独占性、流量控制等特性，更逼近硬件行为，方便进行性能指标的建模和评估。

摘要： 本发明提供了一种基于axi总线的Lvds数据通信实现方法及通信装置，所述通信实现方法包括如下步骤：对Lvds发送模块和Lvds接收模块进行配置；将Lvds发送模块与Lvds接收模块分别与axi总线中的axi_fifo相连；将axi_stream总线输入的数据通过所述axi_fifo挂载至axi_full总线或axi_lite总线上输出，和/或将axi_full总线或axi_lite总线上的输入通过所述axi_fifo转化为axi_stream总线输出，能够将Lvds数据挂载在axi总线上，从而在fpga或zynq上实现Lvds数据通讯。

摘要： 本发明公开了一种基于AXI总线的FlexRay控制器，包括：AXI协议模块、CHI协议模块、BMIF模块、通信控制器、时钟交叉单元、PE协议引擎，CHI总线转换为AXI总线协的转换接口，包括逻辑控制模块、内部缓存FIFO模块、协议转换控制模块。本发明的优点是形成基于AXI总线的FlexRay控制器标准IP，利用该IP可以直接与SoC中AXI总线相接，使用时可以挂接于基于AXI总线的SoC电路中，不再需要进行总线协议转换。而且该IP模块设计时考虑了标准的AXI总线协议与传统的CHI协议，可以应用于原PowerPC处理器领域，也可应用于ARM处理器领域。

摘要： 本发明公开了一种基于AXI总线传输数据的方法，包括：第一设备通过AXI总线向第二设备发送第一数据；第二设备接收第一数据，并向第一设备返回第一响应信号；第二设备通过AXI总线向第一设备发送第二数据；第一设备接收第二数据，并向第二设备返回第二响应信号。本发明还公开了一种基于AXI总线传输数据的装置、计算机设备和可读存储介质。本发明中，基于AXI总线实现两个设备间的数据通信，两个设备均可以主动向对方发送数据，而不用等待数据被读取时才发送，在数据高速传输时可有效减少了传输延迟，提高传输效率，灵活性较高。

摘要： 本发明公开一种基于FSMC和AXI总线的数据隔离加密系统，包括STM32、转换模块、DBram模块、Bram Controller模块、SMX模块和ZYNQ CPU模块，STM32通过FSMC接口与转换模块相连，转换模块与DBram模块相连，DBram模块的另一端与Bram Controller模块，Bram Controller模块用于控制访问时序，Bram Controller模块通过AXI总线连接至SMX模块的AXIM接口，SMX模块的AXIS接口通过AXI总线连接至ZYNQ CPU模块，SMX模块对数据进行加密并将加密后的数据传输至ZYNQ CPU模块。本发明保证数据明文密文物理隔离可保证大批量数据传输中较高吞吐量并且难以监听，从而实现高安全、高性能、可移植的数据隔离加密方法。

摘要： 本申请公开了一种基于AXI总线的通讯方法、装置以及介质，通过AXI总线接收总线信号，之后将总线信号转换为RAM接口信号，根据各外围设备的地址，将RAM接口信号中的地址信号转换为适配各外围设备的精简地址，最后根据各外围设备的精简地址和对应的数据信号通知各外围设备执行对应的动作。采用本技术方案，在接收到AXI总线的总线信号后，对总线信号进行解析，将总线信号转化成适用于RAM接口的RAM接口信号，使更多的外围设备无需再额外开发AXI总线接口，即可实现与处理器通过AXI总线的通信，减少了资源的浪费。并且，对总的地址信号进行优化，减小了信号的大小，可以快速保存数据，提高总线权限的释放速度。

摘要： 本发明适用于芯片技术领域，提供了一种基于AXI总线的芯片内存保护方法，包括：CODEC模块写入数据，CODEC模块向MPM模块写入数据；MPM模块处理数据，所述MPM模块根据被配置不同模块端口合法的访问内存空间范围，对于超出合法范围空间的写操作，将不会透传到AXI总线层次；AXI总线模块数据处理，当CODEC模块将写命令先传输到系统的AXI总线模块上，AXI总线模块根据AW写命令的地址信息将此写操作通过内部译码分发到DDR模块端口；DDR模块数据存储，当AXI总线模块根据AW写命令的地址信息将此写操作通过内部译码分发到DDR模块之后，DDR模块将信息记录。通过增加了一个可配置的内存保护模块，对于超出合法范围空间的写操作，将不会透传到AXI总线层次，从而阻止了写DDR空间。

摘要： 本发明公开了一种PCIE总线与AXI总线的桥接系统，包括第一桥接模块、第二桥接模块和第三桥接模块；第一桥接模块，用于进行User寄存器的读写配置。第二桥接模块，用于将由AXI总线发送过来的AXI格式的输入数据流转换为PCIE格式传输至PCIE总线，完成输入数据流从AXI格式向PCIE格式的转换。第三桥接模块，将用于将PCIE总线发送过来的PCIE格式的输出数据流转换为AXI格式传输至AXI总线，完成输出数据流从PCIE格式向AXI格式的转换。通过实施本发明能够降低User端的控制复杂度，并提高数据传输效率。

摘要： 本申请提供的一种基于AXI协议的总线通信方法及装置，支持多数据同时访问，利用存储控制模块对访问数据进行缓存。利用第一多路选择器和第二多路选择器为数据选择输入端口或输出端口。利用第一总线互联模块和第二总线互联模块对数据传输顺序进行限定，同时根据寄存器内储存的从设备编号对目标数据进行校验保证了数据传输的有序性和准确性。结合存储控制模块中设置的预取空间与仲裁器内置的数据传输优先级判断规则省去了主设备在访问从设备时，需要等待访问数据结果回执再进行下一次访问的步骤，提升了数据交换的效率。