METHOD FOR PREPARING A DISPERSION SYSTEM STABILISED BY NANOPARTICLES OF FREEZE-DRIED PLA THAT HAVE UNDERGONE THERMAL ANNEALING, AND THE DISPERSION SYSTEM, SUITABLE FOR USE AS AN EMULSIFIER FOR PRODUCTS FOR HUMAN OR ANIMAL CONSUMPTION

摘要

The present invention relates to a method for preparing a micrometric dispersion system, which is stabilised using the Pickering method and is biodegradable and surfactant-free, which comprises stabilising a water-in-oil (W/O) emulsion with polymer nanoparticles (NPs) based on biodegradable lactic-acid-derived polymers, in a continuous water phase containing polymer NPs based on biodegradable hydrophilic polymers derived from lactic acid/glycolic acid, wherein the NPs are selected from NPs of polylactic acid (PLA) and polylactic-co-glycolic acid (PLGA), respectively. Such polymer NPs are prepared using the anti-solvent technique, without using any surfactant. The PLA NPs undergo freeze-drying and thermal annealing, and the dispersion system can be freeze-dried and then reconstituted in water to obtain an encapsulation system. The invention also relates to the micrometric dispersion system, suitable for use as an emulsifier for products for human or animal consumption or use.