首页> 外国专利> METHOD FOR THE TREATMENT OF CHRONIC HEART FAILURE IN YOUNG CHILDREN WITH A DILATED PHENOTYPE OF CARDIOMYOPATHY

METHOD FOR THE TREATMENT OF CHRONIC HEART FAILURE IN YOUNG CHILDREN WITH A DILATED PHENOTYPE OF CARDIOMYOPATHY

机译:扩张型心肌病幼儿慢性心力衰竭的治疗方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to pediatric cardiology, and can be used in infants with a dilated cardiomyopathy (CMP) phenotype. On the first day, ACEI inhibitors are prescribed at a dose of 1/10 of the therapeutic dose, the next day, BBA is prescribed, also starting from 1/10 of the therapeutic dose. Then the dose of ACEI inhibitor captopril is increased on the 3rd, 5th, 7th, 9th, 11th, 13th day, and the dose of ACEI inhibitor enalapril is increased on the 3rd, 5th, 7th, 9th, 11th day. The dose of BBA carvedidol or bisoprolol is increased on the 4th, 6th, 8th, 10th, 12th day. At the same time, the patient's body weight, the amount of fluid consumed and excreted, respiratory rate, heart rate are monitored daily, the presence of hepatomegaly is assessed, the rule of alternating days of raising doses and ACEI and BBA is observed.;EFFECT: method makes it possible to increase the effectiveness of CHF treatment in children with a dilated phenotype of CMP by prescribing therapy with the main pathogenetic drugs and the optimal rate of drug dose titration in stationary conditions.;1 cl, 4 tbl, 2 ex
机译:领域:医学。;物质:本发明涉及医学,即儿科心脏病学,可用于具有扩张型心肌病(CMP)表型的婴儿。第一天,ACEI抑制剂的剂量为治疗剂量的1/10,第二天,BBA的剂量为治疗剂量的1/10。然后在第3、5、7、9、11、13天增加ACEI抑制剂卡托普利的剂量,在第3、5、7、9、11天增加ACEI抑制剂依那普利的剂量。BBA卡维地多或比索洛尔的剂量在第4、6、8、10、12天增加。同时,每天监测患者的体重、消耗和排出的液体量、呼吸频率、心率,评估是否存在肝肿大,观察增加剂量的交替天数以及ACEI和BBA的规律。;效果:该方法通过使用主要致病药物和在固定条件下的最佳药物剂量滴定率来提高扩张型CMP儿童CHF治疗的有效性。;1 cl,4 tbl,2 ex

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