A CONTRAST AGENT FOR CHEMICAL EXCHANGE SATURATION TRANSFER MAGNETIC RESONANCE IMAGING, AND A CHEMICAL EXCHANGE SATURATION TRANSFER MAGNETIC RESONANCE IMAGING METHOD USING THE SAME

摘要

The present invention relates to a contrast medium for saturation transition magnetic resonance imaging (CEST MRI) by chemical exchange and a method for saturation transition magnetic resonance imaging by chemical exchange using the same, wherein the contrast agent for CEST MRI is biguanide and derivatives thereof It includes any one compound selected from the group consisting of. The contrast agent for CEST MRI may image acidity by using CEST characteristics resulting from the chemical structure of the biguanide-based drug.