Pharmaceutical composition for the treatment of hypoxic ischemic encephalopathy comprising mesenchymal stem cell line expressing brain-derived neurotrophic factor

摘要

The present invention relates to the treatment of hypoxic ischemic encephalopathy (HIE) of stem cells expressing brain-derived neurotrophic factor, and the pharmaceutical composition for treating HIE of the present invention can be mass-produced, and the same BDNF is expressed as a stem cell capable of maintaining the effect, and in particular, the stem cell has a high cell proliferation rate as an immortalized mesenchymal stem cell, but has a low possibility of abnormal differentiation and proliferation, and thus has high stability, so a therapeutic pharmaceutical composition for HIE can be usefully used as