THREE-DIMENSIONAL CHOROIDAL VESSEL IMAGING AND QUANTITATIVE ANALYSIS METHOD AND APPARATUS BASED ON OPTICAL COHERENCE TOMOGRAPHY SYSTEM

摘要

A three-dimensional choroidal vessel imaging and quantitative analysis method and apparatus based on optical coherence tomography (OCT). The method comprises: on the basis of the idea of reverse compensation of an OCT backscattering signal, performing reverse compensation on backscattering attenuation signals of a deep choroidal vessel and a matrix acquired by means of OCT, so as to enhance a signal-to-noise ratio of the choroidal vessel; after an enhanced OCT choroidal image signal is acquired, further using a segmentation method based on deep learning to perform intelligent segmentation on a boundary between a choroid and a retinal epithelial layer and a boundary between the choroid and a sclera, thereby overcoming the defects of a traditional algorithm consuming time and being low in accuracy in three-dimensional choroid boundary segmentation; and on the basis of boundary segmentation, further using an improved adaptive threshold segmentation method to automatically separate three-dimensional choroidal vessel and non-vessel tissue, and according to the distribution and proportion of the vessels in an image in a three-dimensional volume space, calculating global and regional quantitative indexes which can characterize choroidal ischemia.