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CRF1 receptor antagonists for treating congenital adrenal hyperplasia, their pharmaceutical preparations and solid forms

机译:CRF1受体拮抗剂治疗先天性肾上腺增生,其药物制剂和固体形式

摘要

4 - (4 - (2-chloro-4-methoxy-5-methylphenyl) - N - ((1s) - 2-cyclopropyl-1 - (3-fluoro-4-methylphenyl) ethyl) - 5-methyl-n-prop-2 - IN-1)3 - containing thiazol-2-2 - amine (formula I) or pharmacally acceptable salt thereof;Providing a method associated with the treatment of congenital adrenal hyperplasia in an object requiring it.Solution furtherIn the treatment of congenital adrenal hyperplasia (CAH)4 - (2-chloro-4-methoxy-5-methylphenyl) - N - ((1s) - 2 - cyclopropyl-1 - (3-fluoro-4-methylphenyl) ethyl) - 5-methyl-n-prop-2 - IN-13 - pharmaceutical preparations and solid forms of thiazol-2-amine or pharmaceutically acceptable salt thereofAnd their use is provided.No selection
机译:4 - (4 - (2-氯-4-甲氧基-5-甲基苯基) - N - ((1S) - 2-环丙基-1-(3-氟-4-甲基苯基)乙基) - 5-甲基-N- PROP-2 - IN-1)3 - 含有噻唑-2-2-胺(式I)或其药遗传可接受的盐;提供与需要它的物体中先天性肾上腺增生的方法。培育物的治疗方法进一步 先天性肾上腺增生(CAH)4 - (2-氯-4-甲氧基-5-甲基苯基) - N - ((1S) - 2 - 环丙基-1-(3-氟-4-甲基苯基)乙基) - 5-甲基 -N-PROP-2 - 13 - 13 IN-13-药物制剂和固体形式的噻唑-2-胺或其药学上可接受的盐及其使用。NO选择

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