MASS PRODUCTION METHOD FOR CRONOBACTER SAKAZAKII BACTERIOPHAGE

摘要

The present invention relates to a method for mass production of bacteriophages, specifically Cronobacter sakazakii bacteriophages, and specifically, the present invention consists of a two-stage self-cycling (TSSC) process, By adding a nutrient medium necessary for the culture of Chronobacter sakazaki and measuring the pH change of the culture medium, the optimal bacteriophage inoculation time and harvest time can be set. Continuous mass production is possible.