METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING MYOPIA WITH S-METHYL-L-THIOCITRULLINE, A SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE (NNOS) INHIBITOR, AND DERIVATIVES THEREOF

摘要

. The disclosure relates to methods and compositions for preventing and/or treating an ocular disease. In particular, the disclosure relates to preventing and/or treating myopia with systemic or topical administration of S-methyl-L-thiocitrulline hydrochloride, which is a selective neuronal nitric oxide synthase (nNOS) inhibitor, or a derivative thereof.