Method for estimating breast cancer cell abundance

摘要

The present invention provides improved accuracy of indicators for predicting the effect of drug therapy on breast cancer. Specifically, the present invention provides a method for estimating the abundance of breast cancer cells, including the following (1) and (2): (1) in a sample derived from a human subject, the following: (a) SEQ ID NO: 1. Cytosine residues in the CG moiety consisting of the 1000th and 1001st nucleotides in the nucleotide sequence of SEQ ID NO: 2; (b) Cytosine residues in the CG moiety consisting of the 1000th and 1001st nucleotides in the nucleotide sequence of SEQ ID NO: 2; ) Cytosine residues in the CG moiety consisting of the 1001st and 1002nd nucleotides in the nucleotide sequence of SEQ ID NO: 3; or (d) analyzing the methylation rate of these combinations; and (2) (1). To estimate the abundance of breast cancer cells in human subject-derived samples based on the methylation rate obtained.