首页>
外国专利>
PEPTIDE HAVING CYTOPROTECTIVE EFFECT AGAINST ENVIRONMENTAL POLLUTANT AND USE THEREOF
PEPTIDE HAVING CYTOPROTECTIVE EFFECT AGAINST ENVIRONMENTAL POLLUTANT AND USE THEREOF
展开▼
机译:具有细胞保护作用的肽对环境污染物和其用途
展开▼
页面导航
摘要
著录项
相似文献
摘要
Provided are a peptide with a cytoprotective effect against environmental pollutants and a use thereof. The peptide consisting of an amino acid sequence of SEQ ID NO: 1, 2, or 3 directly binds to 2,3,7,8-tetrachlorodibenzo-p-dioxin (hereinafter, referred to as TCDD), known as being the most toxic among the class of dioxins, to prevent dermal penetration and the activation mechanism of AhR by TCDD and polycyclic aromatic hydrocarbons contained in fine dust. Such a direct cytoprotective effect against environmental pollutants is distinguished from preexisting methods that are configured to indirectly block opportunities to contact these materials or to reduce toxicity through barrier reinforcement.
展开▼
机译:提供了一种肽,其具有对环境污染物的细胞保护作用及其用途。 由SEQ ID NO:1,2或3的氨基酸序列组成的肽直接与2,3,7,8-四氯二氯胺-P-二恶蛋白(下文称为TCDD)直接结合,称为最有毒 在二恶英的类中,为了防止皮肤干燥的皮肤渗透和AHR的活化机制和细粉尘中含有的多环芳烃。 这种针对环境污染物的直接细胞保护作用与预先存在的方法区分开来,该方法被配置为间接地阻挡机会接触这些材料或通过屏障加固来减少毒性。
展开▼