Influenza treatment with substituted polycyclic pyridone derivatives and prodrugs thereof in subjects with influenza and risk factors for complications

摘要

Methods of treating influenza virus infection are described. The disclosed methods generally involve administering an effective amount of a compound, eg, baloxavir marboxil, to a subject having influenza virus infection and at least one risk factor for complications. In general, the amount is effective such that the reduction in time to amelioration of at least one symptom of influenza virus infection is statistically significant compared to that of an untreated subject.