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ACTIVITY BASED HOST CELL PROTEIN PROFILING
ACTIVITY BASED HOST CELL PROTEIN PROFILING
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机译:基于活性的宿主细胞蛋白质分析
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摘要
The present application provides methods and systems for identifying host cell protein impurities which have enzymatic activities in biopharmaceutical products and in samples during manufacturing processes. The present application provides various activity-based probes to characterize different enzyme classes of host cell protein impurities including probes containing functionalized molecules with reporter or affinity-based tags.
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