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METHOD FOR PROMOTING DIVERSIFICATION OF ANTIBODY VARIABLE REGION
METHOD FOR PROMOTING DIVERSIFICATION OF ANTIBODY VARIABLE REGION
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机译:促进抗体可变区多样化的方法
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摘要
The present invention relates to a method for promoting diversification of variable regions of an antibody. Specifically, the present invention relates to a method for promoting diversification of the amino acid sequences of variable regions of an antibody generated by an avian B cell population, wherein the method comprises suppressing the PI3Kα activity of each avian B cell comprised in the avian B cell population expressing the antibody.
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