A method for the detection of diseases from EB virus related NK cell lymphoproliferative disease to NK cell tumor progression

摘要

Problem to be solved: to provide a measurement method for assisting the progress of progress to the disease leading to EB virus related NK cell lymphoproliferative disease and / or NK cell tumor progress.On the collected biological specimenAs a multi markerAt least we measured the expression of Cycas (cyclin-a2) geneCyclin-B,Cyclin-dCyclin-E 2CDK2CDK4CDC 25A,P53P21CHK1CHK2BCL2L12SurvivinIAPBaxTrilrFAASSHP2,JAK3,STAT3NRASSOCS 3CIS,One or more gene expression levels selected from each gene ofWhen the expression level of each gene is higher than the expression level for the biological specimen collected from the healthy person, it isIt is judged that the progress to the disease is progressively progressing.Diagram