首页> 外国专利> METHODS AND COMPOUNDS FOR PREVENTING AND ARRESTING COVID-19 MORBIDITY AND MORTALITY, VIA INHIBITION OF INTERLEUKIN-6, TNF-ALPHA, AND OTHER CYTOKINES, AND VIA REDUCTION OF C-REACTIVE PROTEINS

METHODS AND COMPOUNDS FOR PREVENTING AND ARRESTING COVID-19 MORBIDITY AND MORTALITY, VIA INHIBITION OF INTERLEUKIN-6, TNF-ALPHA, AND OTHER CYTOKINES, AND VIA REDUCTION OF C-REACTIVE PROTEINS

机译:通过抑制白细胞介素-6,TNF-α和其他细胞因子,以及通过减少C反应蛋白,方法和化合物

摘要

Methods and compounds for preventing and arresting COVID-19 morbidity and mortality, via inhibition of Interleukin-6, TNF-alpha, and other cytokines, and via reduction of C-reactive proteins are provided. Analyses of patients with COVID-19 complicated by ARDS, for example, show highly activated cytotoxic T-cells, resulting from hyperactivation of the immune system. A significant surge of Interleukin-6 (IL-6), TNF-α, and other cytokines are thought to be mediators of this enhanced T-cell activity, and runaway inflammation that are dangerous or fatal to the patient. Example oral formulations dubbed BV-4051 and Artovid-20 provide prophylaxis and treatment of these conditions caused by COVID-19 disease. The example formulations contain plant extracts boosting the human immune system and targeting the detrimental effects of the SARS-CoV-2 virus in its various strains.
机译:通过抑制白细胞介素-6,TNF-α和其他细胞因子的方法和化合物,用于预防和抑制Covid-19发病率和死亡率,以及通过降低C-反应蛋白质的抑制作用。 通过ARDS的Covid-19复杂的患者分析,例如,显示出高度活化的细胞毒性T细胞,由免疫系统的超动激活产生。 白细胞介素-6(IL-6),TNF-α和其他细胞因子的显着浪涌被认为是这种增强的T细胞活性的介质,并且对患者危险或致命的失控炎症。 实施例口服配方被称为BV-4051和Artovid-20提供预防和治疗由Covid-19疾病引起的这些病症。 实施例制剂含有植物提取物,促进人免疫系统,并针对SARS-COV-2病毒在其各种菌株中的不利影响。

著录项

  • 公开/公告号US2021338765A1

    专利类型

  • 公开/公告日2021-11-04

    原文格式PDF

  • 申请/专利权人 BIOVED PHARMACEUTICALS INC.;

    申请/专利号US202117306937

  • 申请日2021-05-03

  • 分类号A61K36/9066;A61K36/268;A61K36/324;A61K45/06;A61K31/375;A61K31/315;A61K31/197;A61K31/25;

  • 国家 US

  • 入库时间 2022-08-24 22:05:31

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