首页> 外国专利> A method for obtaining an index for testing the onset or risk of developing bone marrow tumor in humans, a method for obtaining an index for predicting the presence or future occurrence of a somatic mutation of the DDX41 gene in humans, and for these tests or predictions. kit

A method for obtaining an index for testing the onset or risk of developing bone marrow tumor in humans, a method for obtaining an index for predicting the presence or future occurrence of a somatic mutation of the DDX41 gene in humans, and for these tests or predictions. kit

机译:获得用于测试人类骨髓肿瘤的发作或风险的指标的方法,一种获得用于预测人类中DDX41基因的体细胞突变的索引的指标,以及这些测试或预测 。 成套工具

摘要

To provide a means for examining the onset or onset risk of a bone marrow tumor in a human, especially of the yellow race.SOLUTION: According to the present invention, a method for obtaining an index for examining the onset or onset risk of a bone marrow tumor in a human comprises detecting one or more germ cell mutations in the DDX41 gene which are mutations in one or more amino acids selected from those at positions 500, 259, 363, 364, 3, 7, 35, 187 and 256 of the amino acid sequence set forth in SEQ ID NO:2 of a polypeptide encoded by the wild-type DDX41 gene.SELECTED DRAWING: Figure 5
机译:提供一种方法,用于检查骨髓肿瘤在人中骨髓肿瘤的发作或发育风险的手段,尤其是黄色种族。溶液:根据本发明,获得用于检查骨骼发病或发病风险的指数的方法 人中的骨髓肿瘤包括检测DDX41基因中的一种或多种生殖细胞突变,其在一个或多个氨基酸中选择选自500,259,363,364,3,7,35,187和256的氨基酸中的突变 由野生型DDX41基因编码的多肽的SEQ ID NO:2中列出的氨基酸序列。选择图:图5

著录项

  • 公开/公告号JP6952376B2

    专利类型

  • 公开/公告日2021-10-20

    原文格式PDF

  • 申请/专利权人 国立大学法人京都大学;

    申请/专利号JP20200131453

  • 发明设计人 小川 誠司;牧島 秀樹;吉田 健一;

    申请日2020-08-03

  • 分类号C12Q1/6827;G01N33/50;G01N33/574;C12Q1/6886;C12N15/52;

  • 国家 JP

  • 入库时间 2022-08-24 21:46:15

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号