Aggregation of gold nanoparticles, gold nanoparticle dispersion, sensitization agent for radiotherapy and method for producing gold nanoparticle dispersion

摘要

Problem to be solved: to provide a method of manufacturing a gold nanoparticle agglomerate capable of dispersing in an electrolyte solution, a gold nanoparticle dispersion solution, a sensitizing agent for radiotherapy and a gold nanoparticle dispersion solution, which can be produced without prolonged enrichment preparation.Aggregates of gold nanoparticles of the present invention that can be dispersed in an electrolyte solution areThe surface of gold nanoparticles is coated with a coating agentCovering agentHydroxyalkanethiol andContains polyethylene glycol having thiol groups at the end of the polyethylene glycol chainThe poly (ethylene glycol) chain of poly (ethylene glycol) interacts with each other in an electrolyte solution to form clusters of agglomerated aggregates which maintain a predetermined spacing.Diagram