v3 Integin v3-targeted probe for diagnosing retinochoroidal neovascular disease and method for manufacturing the same

摘要

Provided are an integrin-targeting probe that can be usefully used in the diagnosis or treatment of retinal choroidal neovascularization or age-related macular degeneration by predicting the occurrence and recurrence of retinal choroidal neovascularization before the structural change of retinal choroidal neovascularization, and a method for preparing the same. This integrin-targeting probe is an integrin α v β 3 targeting probe for diagnosing retinal choroidal neovascular disease, and consists of a fluorescent substance-labeled cyclic RGD peptide completed by conjugating an NH 2 -cyclic RGD peptide precursor to a fluorescent substance. can