Galectin-3 Governs and Coordinates ESCRT and Autophagic Responses During Endomembrane Damage

摘要

The present invention is directed to the discovery that Galectin-3 (Gal3) governs and coordinates ESCRT and autophagic responses in subjects and that compositions and methods of treatment can make use of this discovery in the treatment of autophagy mediated disease states and/or conditions.