Method for promoting cell attachment and regeneration of macrophages and promotion of cell adhesion and regeneration by macrophages

摘要

Problem to be solved: to provide a method to promote cell adhesion and regeneration polarization of macrophages.It is characterized that the integrin bond ligand peptide is negatively charged, including a core containing magnetic nanoparticles, a coating layer that is provided to enclose the core and incorporate an integrin attached ligand peptide Nano ligands for cell attachment and regeneration promotion of macrophages are provided.In order to promote the cell attachment and regeneration of macrophages, it is possible to control the sliding of the nano ligand spatially and spatially by applying a magnetic field to the substrate containing the nano ligand, and the reversible control is possible Magnetic field based spatiotemporal control can efficiently regulate cell adhesion and phenotype of macrophages in vitro and in vivo.Diagram