METHOD FOR CALCULATING CORONARY ARTERY FRACTIONAL FLOW RESERVE ON BASIS OF MYOCARDIAL BLOOD FLOW AND CT IMAGES

摘要

A method for calculating coronary artery fractional flow reserve includes determining myocardial volume by extracting myocardial images; locating a coronary artery inlet and accurately segmenting coronary arteries; generating a grid model required for calculation by edge detection of coronary artery volume data; determining myocardial blood flow in a rest state and CFR by non-invasive measurement; calculating the total flow at the coronary artery inlet in a maximum hyperemia state; determining the flow in different blood vessels in the coronary artery tree in the maximum hyperemia state and then determining flow velocity V1 in the maximum hyperemia state; using V1 as the flow velocity at the coronary artery inlet and calculating a pressure drop ΔP from the coronary artery inlet to a distal end of a coronary stenosis, and a mean intracoronary pressure Pd at the distal end of the stenosis Pd=Pa−ΔP, and calculating fractional flow reserve.