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Intensity modulated proton therapy (IMPT) plan optimization based at least on internal organ anticipated movement and/or expected deformation
Intensity modulated proton therapy (IMPT) plan optimization based at least on internal organ anticipated movement and/or expected deformation
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机译:强度调制质子疗法(IMPT)至少基于内器的预期运动和/或预期变形计划优化
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摘要
A method includes generating a nominal dose distribution based on an image and clinical goals. The method further includes generating a setup error dose distribution based on range and setup uncertainties. The method further includes generating a dose distribution for a parameter of an internal organ. The method further includes optimizing a planned dose distribution of an intensity modulated proton therapy plan by minimizing a total objective value including the nominal dose distribution, the setup error dose distribution dose distribution, and the dose distribution for the internal organ. The method further includes generating a final dose distribution for the intensity modulated proton therapy plan based on beam parameters of the optimized planned dose distribution. The method further includes controlling a proton therapy apparatus configured to deliver proton therapy based on the intensity modulated proton therapy plan with the optimized planned dose distribution.
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