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VECTOR FOR EXPRESSING HUMAN EPIDERMAL GROWTH FACTOR OR SKIN-PERMEABLE HUMAN EPIDERMAL GROWTH FACTOR, AND MICROALGAE TRANSFORMED WITH VECTOR
VECTOR FOR EXPRESSING HUMAN EPIDERMAL GROWTH FACTOR OR SKIN-PERMEABLE HUMAN EPIDERMAL GROWTH FACTOR, AND MICROALGAE TRANSFORMED WITH VECTOR
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机译:向量表达人体表皮生长因子或皮肤渗透人表皮生长因子,和微藻与载体转化
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摘要
The present specification relates to: a vector comprising a promoter of SEQ ID NO: 1 and a human epidermal growth factor (hEGF) exon, which includes a gene coding for hEGF; microalgae transformed with the vector; a method for producing a hEGF protein and/or a PTD-hEGF protein by using the transformed microalgae; and a cosmetic composition containing the hEGF and/or PTD-hEGF protein(s) produced according to the production method. The hEGF and PTD-hEGF proteins, produced according to an aspect of the present invention, can fundamentally block the risk of endotoxicity, unlike a hEGF protein produced from conventionalthereby being usable as a raw material for eco-friendly cosmetic products.
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机译:本说明书涉及:包含SEQ ID NO:1的启动子和人表皮生长因子(HEGF)外显子的载体,其包括用于HEGF的基因编码; 微藻用载体转化; 通过使用转化的微藻制备HEGF蛋白和/或PTD-HEGF蛋白的方法; 和含有根据生产方法制备的HEGF和/或PTD-HEGF蛋白质的化妆品组合物。 根据本发明的一个方面,生产的HEGF和PTD-HEGF蛋白可以从根本上抑制内毒性的风险,与由常规的常规生产的HEGF蛋白是可用作环保化妆品的原料。
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