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METHOD FOR FOCAL BRACHYTHERAPY FOR PROSTATE CANCER IN PATIENTS WHO HAVE UNDERGONE LOW-DOSE INTERSTITIAL BRACHYTHERAPY

机译:患有低剂量间质近距离放射治疗的患者前列腺癌的局灶性近距离放射治疗方法

摘要

FIELD: medicine. ;SUBSTANCE: invention relates to medicine, namely to oncourology and radiology. The diagnosis is carried out at the stage of planning the procedure, a pararectal biopsy of the prostate gland is performed. The radiation dose, the number of microcapsules for implantation and the nature of their distribution during implantation are determined, microcapsules with radionuclide I-125 are implanted with pararectal access into the prostate tumor tissue using a stereotactic attachment with holes. At the same time, the radiation dose, the number of microcapsules for implantation and the nature of their distribution during implantation are determined by the results of a preliminary targeted pararectal biopsy of the prostate performed using combined MRI and CT images during diagnosis. The data showing through which points the biopsy needles were carried out, are stored and used during focal brachytherapy for the installation of microcapsules containing radionuclide I-125 in the prostate gland, carried out under the control of CT. In particular, the holes of the stereotactic prefix are made at 2.5 mm increments. ;EFFECT: method makes it possible to ensure the maximum radiation load directly in the tumor focus, taking into account its malignancy potential, which will ensure an increase in the relapse-free and overall survival of patients with localized forms of prostate cancer against the background of a decrease in the irradiation of healthy tissues, which in turn will not adversely affect the quality of life of patients. ;1 cl, 3 ex
机译:领域:医学。 ;物质:本发明涉及医药,即oncourology和放射。诊断是在规划过程的阶段中进行,进行前列腺的直肠旁活检。的辐射剂量,微胶囊用于植入的数量和它们的分布的注入时的性质被确定,放射性核素I-125微胶囊与直肠旁接成使用具有孔的立体定向附件的前列腺肿瘤组织植入。与此同时,辐射剂量,微胶囊用于植入的数量和它们的分布的注入时的性质是由前列腺的初步目标直肠旁活检的结果确定诊断时使用组合的MRI和CT图像进行。示出了穿过其指向所述活检针进行了数据,被存储和焦近距离放射治疗过程中为安装含放射性核素的I-125在前列腺,CT的控制下进行的微胶囊的使用。特别地,立体定向前缀的孔为2.5mm的增量制成。 ;有效:方法使得能够直接确保最大辐射负载在肿瘤焦点,考虑到其恶性潜力,这将确保在患者的无复发生存率和总生存率的增加与前列腺癌的映衬局部形式在健康组织中,这反过来将不是患者的生活质量产生不利影响的照射下降。 1 CL,3离

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