PHARMACEUTICAL COMPOSITION COMPRISING THE EXTRACT OF BLACK SOLDIER FLY AS AN EFFECTIVE COMPONENT FOR PREVENTION OR TREATMENT OF THROMBOSIS AND HEALTH FUNCTIONAL FOOD COMPRISING THE SAME

摘要

The present invention relates to an antithrombotic composition containing an extract of Hermetia illucens as an active ingredient, and more specifically, the larvae, pupae, dragon horn (shell after pupa molting) and adult extracts of the larvae, pupae, and adult larvae of A. It relates to a pharmaceutical composition and health functional food for preventing or treating / improving thrombosis containing The extract of Dongae, etc. as an active ingredient of the pharmaceutical composition and health functional food for the prevention or treatment of thrombosis of the present invention, as demonstrated through the Examples of the present specification, by inhibition of thrombus formation-related enzymes and blood clotting factors It exhibits strong antithrombotic activity and antithrombotic effect according to inhibition of human platelet aggregation. At low concentrations of 0.5 mg/ml or less, hemolytic activity on human red blood cells is very insignificant, thermal stability is excellent, and acidity at pH 2 Since there is no loss of thrombus formation-related enzymes and blood clotting factor inhibitory effects even in conditions and plasma, it is expected that it can be used for the prevention and treatment of thrombosis such as ischemic stroke and hemorrhagic stroke by improving blood circulation, and the active ingredient is the extract It is a very useful invention in the pharmaceutical and food industries because it has an excellent effect of being processed into various forms such as , powder, pills, tablets, etc.