首页> 外国专利> METHOD FOR PROLIFERATING NEURAL PROGENITOR CELLS AND COMPOSITION FOR TREATING NERVE DISORDERS CONTAINING PROLIFERATED NEURAL PROGENITOR CELLS

METHOD FOR PROLIFERATING NEURAL PROGENITOR CELLS AND COMPOSITION FOR TREATING NERVE DISORDERS CONTAINING PROLIFERATED NEURAL PROGENITOR CELLS

机译:用于治疗含有增殖神经祖细胞的神经障碍的神经祖细胞和组合物的方法

摘要

The present invention provides a method for proliferating neural progenitor cells and a composition for treating neurological diseases, the composition including a proliferated neural progenitor cell. When a fetal neural progenitor cell is cultured under a hypoxia condition and/or in a medium containing tocoperol, tocoperol acetate, or a mixture thereof, the improved cell proliferation rates of the fetal neural progenitor cell are confirmed. In addition, considering an effect of the neural progenitor cell on preventing differentiation thereof into neurons at the time of proliferation, the present disclosure may contribute to mass production of neural stem cells, and accordingly, the proliferated neural progenitor cell is expected to be utilized in the treatment of a neurological disease.
机译:本发明提供了一种增殖神经祖细胞和用于治疗神经疾病的组合物的方法,该组合物包含增殖神经祖细胞。当在缺氧条件下培养胎儿神经祖细胞和/或在含有生育糖醇的介质中培养,乙酸乙酸盐或其混合物,确认胎儿神经祖细胞的改善的细胞增殖率。此外,考虑到神经祖细胞对增殖时预防其进入神经元的神经元的效果,本公开可以有助于批量生产神经干细胞,因此,预计将利用增殖的神经祖细胞。治疗神经疾病。

著录项

  • 公开/公告号EP3205717B1

    专利类型

  • 公开/公告日2021-07-21

    原文格式PDF

  • 申请/专利权人

    申请/专利号EP20140903548

  • 发明设计人 MOON JI-SOOK;LEE HYUN-SEOB;SHIN YEON-HO;

    申请日2014-10-10

  • 分类号C12N5/079;A61K35/12;C12N5/078;A61P25;C12N5/074;

  • 国家 EP

  • 入库时间 2022-08-24 20:02:49

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