Inhibitor of myocardin related transcription factor and serum response factor (mrtf / SRF) mediated gene transcription and use thereof

摘要

In this document, inhibitors of gene transcription mediated by myocardin-related transcription factors and serum response factors, or both myocardin-related transcription factors and serum response factors ("MRTF / SRF"), and the treatment or prevention of cancer and fibrosis Methods for using these are disclosed. In particular, disclosed herein are compounds of formula (I) and formula (II) and pharmaceutically acceptable salts thereof, wherein the substituents are as described. [Selection figure] None