首页> 外国专利> Targeting O-acetylated gD2 gangliosides as novel therapeutic and diagnostic strategies for cancer stem cell cancer

Targeting O-acetylated gD2 gangliosides as novel therapeutic and diagnostic strategies for cancer stem cell cancer

机译：靶向O-乙酰化GD2神经节苷脂作为癌症干细胞癌的新疗效和诊断策略

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摘要

Problem to be solved: to provide an antibody that recognizes O-acetylated - gD2 ganglioside to treat cancer stem cell (CSC) cancer.Antibodies for treating CSC cancer with specific structuresA pharmaceutical composition containing the antibodyA method for treating CSC cancer comprising administering said antibody to a patientMethod for diagnosing CSC cancer using the antibodyUse of O-acetylated - gD2 ganglioside as a biomarker for CSC cancerAndProblem to be solved: to provide a method for predicting a response to a treatment with the antibody of a subject suffering from CSC cancer.No selection

机译：要解决的问题：提供识别o-乙酰化 - Gd2神经节苷脂以治疗癌症干细胞（CSC）癌症的抗体。用于治疗CSC癌的CSC癌的抗体，其含有抗体AcationA治疗CSC癌症的方法，包括将所述抗体施用到患者方法中，用于使用O-乙酰化 - Gd2神经节苷脂作为CSC癌症的生物标志物来诊断CSC癌的CSC癌症：到提供一种方法，用于预测对患有CSC癌症的受试者的抗体治疗的响应。NO选择

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公开/公告号JP2021100418A

专利类型
公开/公告日2021-07-08

原文格式PDF
申请/专利权人オージーディー２ファーマ;ユニベルシテドゥナント;
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申请/专利号JP20210043550
发明设计人バークルステファン;コションノーデニス;ドルヴィリウスミレーヌ;ルドウサルジャン－マルク;テルメミカエル;
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申请日2021-03-17
分类号C12N15/13;C12N15/62;C07K16/28;C07K16/46;A61K39/395;A61P35;A61P35/02;C12P21/08;
国家 JP
入库时间 2022-08-24 19:47:38

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