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MASS SPECTROMETRY ASSAY FOR CONGENITAL ADRENAL HYPERPLASIA
MASS SPECTROMETRY ASSAY FOR CONGENITAL ADRENAL HYPERPLASIA
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机译:先天性肾上腺增生的质谱法测定
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摘要
Methods are provided for detecting the amount of one or more CAH panel analytes (i.e., pregnenolone, 17-OH pregnenolone, progesterone, 17-OH progesterone, dehydroepiandrosterone (DHEA), androstenedione, testosterone, deoxycorticosterone, 11-deoxycortisol, and cortisol) in a sample by mass spectrometry. The methods generally involve ionizing one or more CAH panel analytes in a sample and quantifying the generated ions to determine the amount of one or more CAH panel analytes in the sample. In methods where amounts of multiple CAH panel analytes are detected, the amounts of multiple analytes are detected in the same sample injection.
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