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Antibody based reagents that specifically recognize neurodegenerative disease related forms of the protein TDP-43
Antibody based reagents that specifically recognize neurodegenerative disease related forms of the protein TDP-43
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机译:基于抗体的试剂,其特异性地识别蛋白质TDP-43的神经变性疾病相关形式的蛋白质TDP-43
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摘要
The invention relates to antibodies, antibody fragments and binding agents that specifically recognize TDP-43 associated with frontotemporal dementia (FTD), but not TDP-43 associated with amyotrophic lateral sclerosis (ALS) or TDP-43 associated with healthy human brain tissue, and antibodies, antibody fragments and binding agents that specifically recognize TDP-43 associated with ALS, but not TDP-43 associated FTD or TDP-43 associated with healthy human brain tissue.
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