Systems, methods and computer program products for simulating workflows and activities of physical assets using digital twin models. User-defined simulations are performed by selectin digital twin components being analyzed during the simulation, concentrating the analysis on the selectively defined components and bypassing components that will not be simulated. Users can design the digital twin simulation using one or more available digital twin models. The model can be the most current digital twin model, a previous version of a model or a hybridized model comprising components or portions from multiple versions of the available digital twins. Users can further customize simulations by selecting components or sections of the digital twin model to selectively bypass during the simulation or provide overriding values for non-simulated portions of the digital twin which can be used as entry criteria inputted into the next simulated section or component of the digital twin, to complete the simulation.
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