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Method for producing self-assembled engineered tissue induced by target tissue extracellular matrix and preparation of artificial tissue using the same
Method for producing self-assembled engineered tissue induced by target tissue extracellular matrix and preparation of artificial tissue using the same
The present invention relates to a method for manufacturing a self-assembled body induced by an extracellular matrix, and to an artificial tissue manufacturing method using the same, comprising the steps of: (a) decellularizing and powdering the tissue-derived extracellular matrix (ECM); And (b) adding and culturing the decellularized extracellular matrix powder to cells to form a cell-extracellular matrix powder self-assembly. Consisting of a method for manufacturing a self-assembly induced by an extracellular matrix including, the self-assembly has characteristics similar to that of the extracellular matrix tissue, and it is possible to manufacture a three-dimensional artificial tissue having a size of 1 cm or more, making it useful as a cell therapy agent and an artificial tissue implant. There is an effect that can be utilized.
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