首页> 外国专利> Method for producing self-assembled engineered tissue induced by target tissue extracellular matrix and preparation of artificial tissue using the same

Method for producing self-assembled engineered tissue induced by target tissue extracellular matrix and preparation of artificial tissue using the same

机译:通过靶组织细胞外基质产生自组织工程组织的方法,使用相同的人工组织制备

摘要

The present invention relates to a method for manufacturing a self-assembled body induced by an extracellular matrix, and to an artificial tissue manufacturing method using the same, comprising the steps of: (a) decellularizing and powdering the tissue-derived extracellular matrix (ECM); And (b) adding and culturing the decellularized extracellular matrix powder to cells to form a cell-extracellular matrix powder self-assembly. Consisting of a method for manufacturing a self-assembly induced by an extracellular matrix including, the self-assembly has characteristics similar to that of the extracellular matrix tissue, and it is possible to manufacture a three-dimensional artificial tissue having a size of 1 cm or more, making it useful as a cell therapy agent and an artificial tissue implant. There is an effect that can be utilized.
机译:本发明涉及一种用于制造由细胞外基质诱导的自组装体的方法,以及使用相同的人工组织制造方法,包括以下步骤:(a)组织衍生的细胞外基质的脱细胞化和粉末(ECM ); (b)将脱细胞细胞外基质粉添加和培养至细胞以形成细胞 - 细胞外基质粉末自组装。由一种用于制造由细胞外基质诱导的自组装的方法,包括自组装具有与细胞外基质组织类似的特性,并且可以制造尺寸为1cm的三维人造组织或更多,使其可用作细胞治疗剂和人工组织植入物。有一种可以使用的效果。

著录项

  • 公开/公告号KR20210037242A

    专利类型

  • 公开/公告日2021-04-06

    原文格式PDF

  • 申请/专利权人 아주대학교산학협력단;

    申请/专利号KR1020190119617

  • 发明设计人 박도영;윤희웅;

    申请日2019-09-27

  • 分类号C12N5/071;C12N5/077;C12N5/0775;

  • 国家 KR

  • 入库时间 2022-08-24 18:07:27

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